
Mass Spectrometry is a powerful tool for bioreactor monitoring. Changes to the composition of bioreactor or fermenter off-gas provide crucial insight into cellular health and production efficiency. This makes the fast, accurate analysis of CO2, O2, N2, Ar, H2O and other compounds essential for real-time process control.
Extrel MAX300-BIO uses cutting edge quadrupole mass spectrometer technology to quantify bioreactor gases from multiple reactors within the facility and reports the data to the control system in real-time.

Features:
- Measures CO2, O2, N2, H2O, alcohols, contaminants, and more
- Samples without risk of contamination
- Calculates control parameters in real-time (e.g. Respiratory Quotient)
- Provides flow and mass balance data
- Multiport sample systems for up to 80+ reactors
- High precision and accuracy for optimal process automation
- Low maintenance, utilities and calibration required
- Complete method scale-up
- Lab, Pilot, Production
Applications:
Industrial Bioreactors for
• Biofuels
• Ethanol
• Pharmaceutical Products
– Enzymes
– Antibiotics
– Steroids
– Vitamins
• Biomass
• Biopolymers
• Alcoholic Beverages
• Bread Products
• Waste Treatment
Measuring Principle | Quadrupole Mass Spectrometer Technology |
Detectable Compounds | Any Gas or Vapor Sample |
Detection Range | 100% – 10 ppm Standard, 10 ppb with the Electron Multiplier Option* *Documented on Trace Benzene in Air |
Number of Sample Streams | 16, 31, 40, 80+ |
Analysis Rate | < 0.4 Seconds Per Component |
Number of Components | Unlimited |
Number of Analysis Routines | Unlimited |
Number of User Configurable Data Tags | Unlimited |
Analysis Precision | <0.25% Relative Standard Deviation** ** Based on the analysis of 1% Argon |
Stability | <0.5% Relative Standard Deviation Over 30 Days** ** Based on the analysis of 1% Argon |
Dual Filaments | One Active One Spare with Automatic Switch Over |
Maintenance | Typically Two PMs Per Year |
Calibration and Validation | Manual or Fully Automated |
Mass Range Options | 1-200, 300 or 500 amu |
Filter | 19mm High Transmission Quadrupole Filter |
Power Supply | 110VAC, 50/60Hz, Two 15A Circuits 230VAC, 50/60Hz, One 20A Circuits |
Power Consumption | Nominal: 2500 Watts Startup: 2750 Watts Heat Load: 2500 Watts (8000 BTU/h) |
Weight | Standard Enclosure: 190 Kg ATEX Enclosure: 254 Kg Optional Cart: 18 Kg |
Ambient Temperature | -20 ~ 49 deg C With A/C, Cold Start >= 12 deg C |
Area Classification Options | General Purpose Class 1, Division 2 Groups B, C, D, T3 Class 1, Division 1 Groups B, C, D , T3 ATEX Zone 1 or Zone 2, Group II B +H2, T4 |
Additional Utilities | Purge Gas (For Hazardous Area Installations) Base Calibration Requirement: 2 Gas Bottles |
Data System and Communications | System Control Interface Options: Ethernet, RS-422 (4 Wires) Login Security Levels: Administrator, User and Viewer External Communications: Ethernet, Modbus Serial, Digital I/O, Analog I/O, OPC |